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When is IRB approval from a collaborating institution required?

Question: 
When is IRB approval from a collaborating institution required?
Answer: 
  1. When the collaborating institution is unwilling to cede IRB oversight to U-M or U-M is unwilling to serve as the collaborator's IRB-of-Record.
  2. When the interaction/intervention with the human subjects is taking place at the collaborator's institution, the U-M may determine that IRB review at the collaborator's institution is necessary.