You are here

Institutional Biosafety Committee (IBC)

What should I do next?

Working with recombinant DNA or synthetic nucleic acid molecules at BSL1 or BSL2? Register with the IBC

Proposing a human gene transfer project? Obtain NIH/RAC approval as well as review and approval by U-M's IRB and IBC

Research involving recombinant DNA offers tremendous opportunities for improving our understanding of biological mechanisms and processes and for targeting new and more effective therapies for devastating conditions. At the same time, however, this type of research carries inherent safety risks. Working at an appropriate biosafety containment level and with the appropriate safety precautions is essential for mitigating those risks..  

About the Committee:

As mandated by the NIH Guidelines, U-M's Institutional Biosafety Committee is responsible for assessing the biosafety containment level for research involving recombinant DNA and synthetic nucleic acid moledules. The U-M Institutional Biosafety Committee (IBC) oversees:

  • ALL research involving recombinant and synthetic nucleic acid molecules
  • Research requiring BSL3 containment, including work with Select Agents and Toxins (through the BSL3 Subcommittee)
  • Human gene transfer studies (as an ancillary committee to the IRB)

Scope of IBC Authority

The IBC has jurisdiction over research with recombinant or synthetic nucleic acid molecures occurring at the University's Ann Arbor, Dearborn, and Flint campuses, and it may give approval to non-faculty members (i.e., non-UM entities performing work on campus) on a case-by-case basis. The IBC reports to the Vice President for Research as the  executive officer who has authority over the compliance area including appointment authority to the committee. The U-M Office of Research (UMOR) administratively manages the committee.

IBC Charge
IBC Roster

IBC BSL3 Subcommittee

The IBC also has oversight responsibility for federally-regulated Select Agents and Toxins and other research that requires BSL3 containment. Review of this work is performed by the IBC BSL3 Subcommittee, which operates under a separate charge. Investigators planning work with Select Agents should contact Janet Follo, the University's Responsible Official, at 734-647-3133 for more information or to initiate the required review processes.

Researcher Roles & Responsibilities

Compliance with IBC processes is a term and condition of your research at U-M, and funding for projects may be withheld until compliance is established.

Specifically, principal investigators or project directors at U-M are responsible for:

Questions?

For more information about the IBC, call 734-615-3960 or send e-mail to IBCstaff@umich.edu