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U-M HPSCRO Policy
U-M's Policy on Research with Human Pluripotent Stem Cells outlines the approval requirements, guidelines, and procedures for:
- Donating human embryos for derivation of human pluripotent stem cell (hESC) lines
- Donating human tissue (i.e., somatic cells, such as skin, blood, etc.) for derivation of induced pluripotent stem cells (iPSC) lines
- Obtaining already derived hESC or iPSC lines
- Using hESC or iPSC lines for allowable research
U-M's policy follows State of Michigan and federal policies.
The following use of hESC and/or human iPSC lines are not permitted per U-M HPSCRO policy:
- Derivation of new hESC lines by somatic cell nuclear transfer
- Research involving in vitro culture of any intact human embryo 14 days or older
- Research in which hES and/or iPS cells are introduced into non-human primate blastocysts, or introduced into human blastocysts
- Research that involves the breeding of animals into which hES cells have been introduced (at any stage of development)
- Research in which iPS cells have been introduced into animals such that the cells could contribute to the animal's germline.